γ-Amino Butyric Acid (GABA)

Discovery of γ-Amino Butyric Acid (GABA) Cas 56-12-2

γ-Amino butyric acid (GABA) was developed by Japan's ORYZA Oil Chemical Company in the mid-1990s.

• In 2001, it was officially listed as food grade, and in 2005, Taiwan's Health Department listed GABA as food.

• In 2009, China's Ministry of Health listed GABA as a new resource food.

γ-Amino Butyric Acid (GABA) Cas 56-12-2

GABA appears as white crystalline powder and is not optically active.

Melting point 195-204℃ (decomposition), soluble in water, slightly soluble in ethanol and acetone, insoluble in benzene and ether, decomposition will lose water to form pyrrolidone.

Main Food Sources of γ-Amino Butyric Acid (GABA) Cas 56-12-2

Flow Chart of γ-Amino Butyric Acid (GABA)

There are two GABA synthesis and conversion pathways in plants:

①The GABA shunt, in which glutamate is decarboxylated by glutamate decarboxylase (glutamic acid decarboxylase, GAD) to synthesize GABA

②The polyamine degradation pathway (polyamine degradation pathway), in which GABA is formed from polyamine degradation products.

Functoin of γ-Amino Butyric Acid (GABA) Cas 56-12-2

γ-Amino butyric acid (GABA) is a key inhibitory neurotransmitter in the central nervous system with a variety of physiological functions, including:

• Improving sleep quality: ABA can inhibit the central nervous system and has sedative and hypnotic effects to help improve sleep disorders.

• Lower blood pressure: By regulating the central nervous system, GABA helps lower blood pressure, especially beneficial for people with high blood pressure.

• Anxiety reduction: GABA can bind to the anti-anxiety brain receptor and activate it, preventing anxiety-related information from reaching the brain's instruction center, thus producing an anti-anxiety effect.

• Improve memory: GABA can enhance memory by promoting the synthesis of brain neurotransmitters, especially the release of acetylcholine.

• Cardiovascular health: GABA can promote blood vessel dilation and increase blood flow, thus playing a role in preventing cardiovascular and cerebrovascular diseases.

• Improve liver function: GABA can promote the metabolism of liver cells and help the liver detoxify, thus improving liver function.

These functions make GABA have a wide application prospect in pharmaceutical, food and health care and agriculture industries.