2025-07-23
Aging is a natural way. As humans age naturally, exposure to chemicals or radiation will also cause our cells to age, changing or terminating their normal functions. Senescent cells will produce a senescence-associated secretory phenotype (SASP), which will lead to age-related degeneration of physiological functions and a variety of age-related pathological symptoms over time.
In recent years, with the acceleration of global aging, countries around the world have launched a wave of anti-aging research, among which NMN, ergothioneine, and PQQ have become anti-aging stars.
Of course, the efficacy of natural plant active ingredients is also an important force in the field of health and cannot be ignored. On December 6, 2021, Sun Yu's team from the Shanghai Institute of Nutrition and Health, Chinese Academy of Sciences (Postdoctoral Fellow Xu Qixia from the Shanghai Institute of Nutrition and Health and Professor Fu Qiang from Binzhou Medical College are the co-first authors of the paper) published a research paper entitled: The flavonoid procyanidin C1 has senotherapeutic activity and increases lifespan in mice in the journal Nature Metabolism [1].
The research team used a model containing in vitro human prostate cells to screen a group of natural extracts. They found that grape seed extract and its key ingredient, Procyanidin C1 (PCC1), have specific effects on senescent cells, effectively and selectively killing senescent cells while leaving normal cells intact.
As the public's demand for natural anti-aging solutions grows, Originbio has received a request for customized capsules from customers and successfully delivered 204,000 capsules. We look forward to listening to your needs and tailoring solutions for you.
Links:
1. https://nature.com/articles/s42255-021-00491-8
2. https://doi.org/10.1111/acel.12344