GABA Overview: Powder 99% is a high-purity amino acid that functions as a major inhibitory neurotransmitter in the human central nervous system. It is widely used in dietary supplements, functional foods, and beverages for its potential calming, relaxation, and sleep-supporting effects.
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Source of GABA
GABA (Gamma-Aminobutyric Acid) can be sourced naturally or produced via industrial methods:
Natural Source:
Found in foods like fermented soy products (natto, miso), brown rice, tomatoes, and certain teas.
For commercial production, natural fermentation is preferred to maintain “natural” or “organic” labeling.
Industrial Production:
GABA is mainly produced via microbial fermentation or chemical synthesis.
Microbial fermentation is favored in the dietary supplement and functional food industry due to safety, purity, and scalability.
Manufacturing Process
1. Microbial Fermentation Method (Preferred)
This is the most common method for producing high-purity GABA 99%.
Steps:
Strain Selection:
Use specific bacteria like Lactobacillus brevis, Lactobacillus plantarum, or genetically modified E. coli strains that can efficiently convert glutamic acid to GABA.
Fermentation:
Feed the selected bacteria with a carbohydrate source (e.g., glucose) in a controlled environment.
Optimize conditions such as pH, temperature, and oxygen levels for maximum GABA production.
Separation:
Remove bacterial cells and other solids via filtration or centrifugation.
Purification:
Use techniques like ion-exchange chromatography or crystallization to isolate GABA.
Test Item | Specification | Method |
---|---|---|
Appearance | White crystalline powder | Visual Inspection |
Purity (HPLC) | ≥99% | HPLC |
Moisture Content | ≤0.5% | Karl Fischer / Loss on Drying |
Loss on Drying | ≤0.5% | USP/BP Method |
Residue on Ignition | ≤0.1% | USP/BP Method |
Heavy Metals (as Pb) | ≤10 ppm | ICP-OES / AAS |
Arsenic (As) | ≤3 ppm | ICP-OES / AAS |
Cadmium (Cd) | ≤1 ppm | ICP-OES / AAS |
Mercury (Hg) | ≤0.1 ppm | ICP-OES / AAS |
Microbial Limit – Total Plate Count | ≤1000 CFU/g | USP/BP Microbial Test |
Yeast & Mold | ≤100 CFU/g | USP/BP Microbial Test |
E. coli | Negative | USP/BP Microbial Test |
Salmonella | Negative | USP/BP Microbial Test |
Solubility | Soluble in water | Visual / Lab Test |
pH (1% solution) | 5.0 – 6.5 | pH Meter |
Whether you’re just starting in the industry or a well-established brand, our team has the nutraceutical manufacturing expertise and market insights to help you create high-GABA Powder quality nutritional supplements your customers will love.
1.Customized Supplement Development
OriginBio in-house expert team is adept at turning your ideas into expertly formulated nutraceutical supplements. We primarily specialize in custom manufacturing capsule, powder, and tablet supplements.
2.Build Your Brand
Powders: 25KG Packed in eco-friendly Pouches in customized sizes
Capsules & Tablets: Packed in bottles of 60ct, 90ct or 180ct
3.Tailored Flavor Profiles and Colors
Our in-house food scientists will work with you to develop a distinctive custom formula and flavor profile for your powder supplements. We excel in achieving the perfect blend of great taste, nutrient value, and marketability, ensuring that your product captivates consumers. Our expertise extends to understanding how flavors, sweeteners, and colors can enhance or influence a product’s success.
OriginBiois a ISO9001 registered state of the art dietary supplement facility focused on developing, testing, manufacturing and packaging to deliver high quality products to our partners. OriginBio has an expert team of formulators, flavourists, quality control personnel, quality assurance and production specialist. We strive for excellence in supporting global customers with high quality nutraceutical products. As a full turnkey partner, we are focused and committed to help your turn your product idea in to finished goods by delivery greatest manufacturing experience.
GABA 99% can be used at 100–500 mg per capsule/tablet, 50–200 mg per 250 mL beverage, or 100–200 mg per 5 g powdered drink. It blends easily with excipients, flavors, or carriers, and can be combined with L-Theanine, Magnesium, or B vitamins for enhanced relaxation and sleep support. For cosmetics, 0.1–0.5% GABA in gels or creams provides soothing, anti-aging effects
Dietary Supplements
Capsules, tablets, and softgels for stress relief, relaxation, and better sleep.
Can be combined with L-Theanine, Magnesium, or B vitamins for enhanced calming effects.
Functional Foods & Beverages
Added to teas, energy drinks, smoothies, and protein shakes to promote relaxation and mental calm.
Used in powdered drink mixes or ready-to-drink beverages.
Sports & Wellness Products
Supports post-workout recovery and reduces nervous tension.
Often included in wellness powders or relaxation formulas.
Cosmetics / Topical Applications
0.1–0.5% in gels or creams for skin-soothing, anti-aging, and calming effects.
We support supplement distributors, importers, and supplement brand contract manufacturers with a full-service wholesale solution, making it easy to source high-quality ingredients across regions.
1.Consistent Quality & Compliance
FDA, ISO9001, HACCP certified production facilities
Halal & Kosher certification for global markets
Full documentation (COA, MSDS, TDS, Product Data Sheets) for regulatory compliance in EU, FDA (USA), and Asia
2.Flexible Supply & Logistics
Bulk packaging (25kg drums, custom packs on request)
Global shipping partners with fast lead times (air, sea, express)
Localized export experience for USA (FDA), EU (EFSA), and Asia-Pacific regulations
3.Business Support for Distributors
Competitive wholesale pricing & tiered volume discounts
Private label supplement manufacturers/ OEM formulation services
Marketing & technical support to strengthen your brand positioning
Stable long-term contracts with secure supply capacity
Whether you distribute to health supplement brands, online retailers, or local pharmacies, we provide scalable solutions that grow with your business. Contact us today to request a competitive nutraceutical manufacturing price quote.
What is a supplement contract manufacturer?
A supplement contract manufacturer is a third-party facility that can help you manufacture dietary supplements, starting from research, custom formulation, and ingredient sourcing to manufacturing, quality control, and packaging.
What is the cost of manufacturing dietary aupplements?
The cost of manufacturing dietary supplements depends on a variety of factors, including – but not limited to – ingredients, dosage, delivery format, and packaging. Once we have this information, our team can create a custom nutraceutical manufacturing price quote for you to review.
What formats do your products come from and Colors?
Tablets
Gelatin capsules
Softgels capsules
HALAL capsules
Organic capsules
Custom Blends
Acid-Resistant Capsules
Sustained-release capsules
Capsule Size / Colors
Transparent capsules
Opaque capsule
Pearl capsule
Custom capsule color customization
How long until I receive the product?
Production time can vary depending on the formulations, testing requirements, and other specifications of your supplement product. Once our team understands the product you want to create, we can provide you with information about the expected lead times.
What are your MOQ?
Our facility supports smaller clients and new product launches with reasonable MOQs, but you will need to contact our team for specific MOQs for 50,000 for tablets and 30,000 for capsules.
Are the heavymetals within the limits of CA Prop 65?
Heavy metals such as lead, arsenic, mercury, and cadmium are tested for every batch that we produce. We also ensure that our product complies with the California prop 65 regulations for lead content below 0.5 ppm levels.
Are your products sterilized for microbial safety?
Yes. All the powders we produce, are processed using steam sterilization method and complies with FDA standards for microbial safety.
Are your products free from E.coli & Salmonella?
Consumption of products containing E.coli & Salmonella may pose health issues like stomach cramps, abdominal pains, nausea, etc. All of our products are 100% free of E.coli & Salmonella.
Interested in our supplements? Get your personalized quote now!