Keywords: Wholesale DHB Powder Price, Dihydroberberine Powder Bulk, Nutritional gummies manufacturer, Private label supplement manufacturers, Supplement contract manufacturer.
OriginBio has been the leading dietary supplement contract manufacturer for 20 years, and continue to provide customers with the high-quality products.
DHB (Dihydroberberine) Powder 98% is a high-purity derivative of berberine, renowned for its superior bioavailability and enhanced absorption in the human body. Compared to regular berberine, DHB is more effective at supporting healthy glucose metabolism, improving insulin sensitivity, and promoting cardiovascular health. This makes it an ideal ingredient for dietary supplements targeting metabolic balance and overall wellness.
1. Raw Material Selection: High-quality berberine is selected as the starting material.
2. Hydrogenation Reaction: Berberine undergoes a controlled catalytic hydrogenation to produce DHB.
3. Purification: The reaction mixture is purified using solvent extraction and recrystallization to achieve high purity.
4. Filtration & Concentration: The purified DHB is filtered and concentrated under controlled conditions.
5. Drying: The concentrated DHB is dried using low-temperature vacuum drying to preserve bioactivity.
6. Milling & Sieving: The dried DHB is milled to a uniform fine powder and sieved to ensure consistent particle size.
7. Quality Control: Final product is tested for purity, heavy metals, moisture, and microbial contamination.
8. Packaging: Packed in airtight, moisture-proof containers to ensure stability and shelf life.
| Item | Specification |
| Appearance | Fine yellow to light brown powder |
| Purity (HPLC) | ≥98% |
| Molecular Formula | C20H18NO4 |
| Molecular Weight | 342.36 g/mol |
| Solubility | Soluble in DMSO, ethanol; slightly in water |
| Loss on Drying | ≤1.0% |
| Residue on Ignition | ≤0.5% |
| Heavy Metals (Pb, As, Hg, Cd) | ≤10 ppm |
| Microbial Limits | Total Plate Count ≤1000 CFU/g |
| Yeast & Mold ≤100 CFU/g | |
| E. coli, Salmonella: Negative |
Our products are specially formulated from the best raw materials available, and are manufactured in our state-of-the-art facilities. These facilities feature high-tech equipment that allows us to produce large amounts of uniform capsules, chewables, sublinguals, tablets, powders as well as granules.
1.Customized Supplement Development Capsules：
Imprinted Capsules
Colored Capsules
Gelatin Capsules
Softgels Capsules
HALAL Capsules
Organic Capsules
Acid-Resistant Capsules
Sustained-release Capsules
Clear Capsules
Our current capacity for encapsulation is up to 1 billion capsules. We are flexible on batches sizes from low, medium to large scale.
Powders：
Protein Powders
Multi Vitamin & Mineral Blend
Green Food Powders
Collagen
Glucosamine
Meal Replacement
Extruded granule
Our v-blender and w-blender supports our tablet and capsule productions as well as supply us with the ready-to-mix beverage powders. Our current configuration can provide us over 3600 tons annually.
Tablets：
Chewable
Colored Coated Tablets
Sugar Coating
HPMC Coating
Imprinted Tablets
Sublingual tablets
Enteric Coating Tablets
Carved Seal Tablets
Our current configuration can produce up to 4 billion tablets per year
Gummies：
Sugar Free Gummies
Full Sugar Gummies
Reduced Sugar Gummies
Our Nutritional gummies using a state of the art, starch-free manufacturing process. All gummies are 100% plant based (Vegan or Vegetarian).
2.Build Your Brand
Powders: 25KG Packed in eco-friendly Pouches in customized sizes
Capsules & Tablets: Packed in bottles of 60ct, 90ct or 180ct
3.Tailored Flavor Profiles and Colors
Our in-house food scientists will work with you to develop a distinctive custom formula and flavor profile for your powder supplements. We excel in achieving the perfect blend of great taste, nutrient value, and marketability, ensuring that your product captivates consumers. Our expertise extends to understanding how flavors, sweeteners, and colors can enhance or influence a product’s success.
4.Packaging
OriginBio has a full line of various packaging technique at our manufacturing plants. Various bottles, pouches, stick-type packaging, clear wrap packing to name a few. Packaging at our facility will ensure the products stay clean and safe for the
customers.
| Ingredient | Dosage per Serving | Purpose / Benefit |
| DHB Powder 98% | 50–150 mg | Supports healthy glucose metabolism |
| Microcrystalline Cellulose | 100 mg | Filler / Tablet binder |
| Magnesium Stearate | 5 mg | Anti-caking agent |
| Silicon Dioxide | 5 mg | Anti-clumping agent |
| Capsule Shell (Veg/ Gelatin) | 1 capsule | Delivery form |
Duration: For best results, use consistently for 3–6 months to notice visible improvements in skin appearance, hydration, and overall anti-aging benefits.
We support supplement distributors, importers, and supplement brand contract manufacturers with a full-service wholesale solution, making it easy to source high-quality ingredients across regions.
1.Consistent Quality & Compliance
FDA, ISO9001, HACCP certified production facilities
Halal & Kosher certification for global markets
Full documentation (COA, MSDS, TDS, Product Data Sheets)
2.Flexible Supply & Logistics
Bulk packaging (25kg drums, custom packs on request)
MOQ 50,000 for tablets and 30,000 for capsules
Global shipping partners with fast lead times (air, sea, express)
Localized export experience for USA (FDA), EU (EFSA), and Asia-Pacific regulations
3.OEM Contract of Supplements
OriginBio offers excellent skill for supplements OEM to domestic/overseas various companies
OEM/PB supply not only of seamless capsules but also granules, pills, tablets, etc
MOQ 50,000 for tablets and 30,000 for capsules
Fully integrated production from product design to manufacture, filling, and packaging
Whether you distribute to health supplement brands, online retailers, or local pharmacies, we provide scalable solutions that grow with your business. Contact us today to request a competitive nutraceutical manufacturing price quote.
What is a supplement contract manufacturer?
A supplement contract manufacturer is a third-party facility that can help you manufacture dietary supplements, starting from research, custom formulation, and ingredient sourcing to manufacturing, quality control, and packaging.
What is the cost of manufacturing dietary aupplements?
The cost of manufacturing dietary supplements depends on a variety of factors, including – but not limited to – ingredients, dosage, delivery format, and packaging. Once we have this information, our team can create a custom nutraceutical manufacturing price quote for you to review.
How long until I receive the product?
Production time can vary depending on the formulations, testing requirements, and other specifications of your supplement product. Once our team understands the product you want to create, we can provide you with information about the expected lead times.
What are your MOQ?
Our facility supports smaller clients and new product launches with reasonable MOQs, but you will need to contact our team for specific MOQ for 50,000 for tablets and 30,000 for capsules.
Are the heavymetals within the limits of CA Prop 65?
Heavy metals such as lead, arsenic, mercury, and cadmium are tested for every batch that we produce. We also ensure that our product complies with the California prop 65 regulations for lead content below 0.5 ppm levels.
Are your products sterilized for microbial safety?
Yes. All the powders we produce, are processed using steam sterilization method and complies with FDA standards for microbial safety.
Are your products free from E.coli & Salmonella?
Consumption of products containing E.coli & Salmonella may pose health issues like stomach cramps, abdominal pains, nausea, etc. All of our products are 100% free of E.coli & Salmonella.
Interested in our supplements? Get your personalized quote now!
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