Keywords: Wholesale Sodium Hyaluronate Powder Price, Sodium Hyaluronate Powder bulk, Nutritional gummies manufacturer, Private label supplement manufacturers, Capsule manufacturer.
OriginBio has been the leading dietary supplement contract manufacturer for 20 years, and continue to provide customers with the high-quality products.
Sodium hyaluronate is the sodium salt of hyaluronic acid, a naturally occurring polysaccharide found in the human body, primarily in connective tissues, skin, and eyes. It is widely recognized for its exceptional moisture-retaining properties and its ability to support skin hydration, elasticity, and overall health. This high-purity powder (98%) is ideal for cosmetic, pharmaceutical, and nutraceutical applications.
1. Raw Material Preparation
· Source: Typically produced via fermentation of Streptococcus species or extracted from animal tissues (e.g., rooster combs).
· Preparation: Raw material is cleaned and pretreated to remove impurities and proteins.
2. Fermentation (Microbial Production Route)
· Microorganisms (like Streptococcus zooepidemicus) are cultured in nutrient-rich media.
· Controlled conditions: temperature, pH, aeration, and stirring are monitored.
· During fermentation, hyaluronic acid is secreted into the culture broth.
3. Extraction
· The fermentation broth or tissue extract is filtered to remove cells and insoluble matter.
· Hyaluronic acid is precipitated using ethanol or isopropanol, separating it from unwanted proteins and salts.
4. Purification
· Dialysis or ultrafiltration: Removes small molecules, salts, and endotoxins.
· Enzymatic treatment (optional): Degrades residual proteins for higher purity.
· Activated carbon treatment: Removes pigments and impurities for a white, clean product.
5. Conversion to Sodium Hyaluronate
· The purified hyaluronic acid is neutralized with sodium hydroxide (NaOH) to form sodium hyaluronate.
· pH is carefully controlled to prevent degradation.
6. Concentration & Drying
· Concentration: The solution is concentrated under vacuum.
· Drying methods:
7. Sieving & Milling
· Powder is milled to a uniform particle size and passed through fine mesh sieves.
· Ensures consistency and ease of use in applications.
8. Quality Control & Packaging
· QC tests: Purity, moisture content, pH, microbial limits, heavy metals, molecular weight.
Packaging: Sealed in moisture-proof, food-grade containers to maintain stability.
| Parameter | Specification |
| Appearance | White to off-white fine powder |
| Purity | ≥ 98% |
| Moisture Content | ≤ 5% |
| pH (1% solution) | 5.0 – 8.0 |
| Molecular Weight | 100,000 – 2,000,000 Da (customizable) |
| Heavy Metals | ≤ 20 ppm |
| Residual Solvents | Complies with USP standards |
| Microbial Limit | Total Plate Count < 1000 CFU/g |
| Yeast & Mold < 100 CFU/g | |
| E. coli: Negative | |
| Solubility | Easily soluble in water |
Our products are specially formulated from the best raw materials available, and are manufactured in our state-of-the-art facilities. These facilities feature high-tech equipment that allows us to produce large amounts of uniform capsules, chewables, sublinguals, tablets, powders as well as granules.
1.Customized Supplement Development Capsules：
Imprinted Capsules
Colored Capsules
Gelatin Capsules
Softgels Capsules
HALAL Capsules
Organic Capsules
Acid-Resistant Capsules
Sustained-release Capsules
Clear Capsules
Our current capacity for encapsulation is up to 1 billion capsules. We are flexible on batches sizes from low, medium to large scale.
Powders：
Protein Powders
Multi Vitamin & Mineral Blend
Green Food Powders
Collagen
Glucosamine
Meal Replacement
Extruded granule
Our v-blender and w-blender supports our tablet and capsule productions as well as supply us with the ready-to-mix beverage powders. Our current configuration can provide us over 3600 tons annually.
Tablets：
Chewable
Colored Coated Tablets
Sugar Coating
HPMC Coating
Imprinted Tablets
Sublingual tablets
Enteric Coating Tablets
Carved Seal Tablets
Our current configuration can produce up to 4 billion tablets per year
Gummies：
Sugar Free Gummies
Full Sugar Gummies
Reduced Sugar Gummies
Our Nutritional gummies using a state of the art, starch-free manufacturing process. All gummies are 100% plant based (Vegan or Vegetarian).
2.Build Your Brand
Powders: 25KG Packed in eco-friendly Pouches in customized sizes
Capsules & Tablets: Packed in bottles of 60ct, 90ct or 180ct
3.Tailored Flavor Profiles and Colors
Our in-house food scientists will work with you to develop a distinctive custom formula and flavor profile for your powder supplements. We excel in achieving the perfect blend of great taste, nutrient value, and marketability, ensuring that your product captivates consumers. Our expertise extends to understanding how flavors, sweeteners, and colors can enhance or influence a product’s success.
4.Packaging
OriginBio has a full line of various packaging technique at our manufacturing plants. Various bottles, pouches, stick-type packaging, clear wrap packing to name a few. Packaging at our facility will ensure the products stay clean and safe for the
customers.
| Ingredient | Dosage (per serving) | Purpose / Benefit |
| Sodium Hyaluronate Powder 98% | 50 – 200 mg | Supports skin hydration, joint lubrication, and tissue repair |
| Microcrystalline Cellulose (MCC) | q.s. | Filler / tablet binder |
| Magnesium Stearate | 1 – 2 mg | Lubricant for smooth tablet manufacturing |
| Silicon Dioxide | 1 – 2 mg | Anti-caking agent |
| Capsule Shell (if applicable) | 1 | Encapsulation for easy consumption |
Wholesale Sodium Hyaluronate Capsules Low MOQ Supplement Manufacturer USA For best results, use consistently for 3–6 months to notice visible improvements in skin appearance, hydration, and overall anti-aging benefits.
We support supplement distributors, importers, and supplement brand contract manufacturers with a full-service wholesale solution, making it easy to source high-quality ingredients across regions.
1.Consistent Quality & Compliance
FDA, ISO9001, HACCP certified production facilities
Halal & Kosher certification for global markets
Full documentation (COA, MSDS, TDS, Product Data Sheets)
2.Flexible Supply & Logistics
Bulk packaging (25kg drums, custom packs on request)
MOQ 50,000 for tablets and 30,000 for capsules
Global shipping partners with fast lead times (air, sea, express)
Localized export experience for USA (FDA), EU (EFSA), and Asia-Pacific regulations
3.OEM Contract of Supplements
OriginBio offers excellent skill for supplements OEM to domestic/overseas various companies
OEM/PB supply not only of seamless capsules but also granules, pills, tablets, etc
MOQ 50,000 for tablets and 30,000 for capsules
Fully integrated production from product design to manufacture, filling, and packaging
Whether you distribute to health supplement brands, online retailers, or local pharmacies, we provide scalable solutions that grow with your business. Contact us today to request a competitive nutraceutical manufacturing price quote.
What is a supplement contract manufacturer?
A supplement contract manufacturer is a third-party facility that can help you manufacture dietary supplements, starting from research, custom formulation, and ingredient sourcing to manufacturing, quality control, and packaging.
What is the cost of manufacturing dietary aupplements?
The cost of manufacturing dietary supplements depends on a variety of factors, including – but not limited to – ingredients, dosage, delivery format, and packaging. Once we have this information, our team can create a custom nutraceutical manufacturing price quote for you to review.
How long until I receive the product?
Production time can vary depending on the formulations, testing requirements, and other specifications of your supplement product. Once our team understands the product you want to create, we can provide you with information about the expected lead times.
What are your MOQ?
Our facility supports smaller clients and new product launches with reasonable MOQs, but you will need to contact our team for specific MOQ for 50,000 for tablets and 30,000 for capsules.
Are the heavymetals within the limits of CA Prop 65?
Heavy metals such as lead, arsenic, mercury, and cadmium are tested for every batch that we produce. We also ensure that our product complies with the California prop 65 regulations for lead content below 0.5 ppm levels.
Are your products sterilized for microbial safety?
Yes. All the powders we produce, are processed using steam sterilization method and complies with FDA standards for microbial safety.
Are your products free from E.coli & Salmonella?
Consumption of products containing E.coli & Salmonella may pose health issues like stomach cramps, abdominal pains, nausea, etc. All of our products are 100% free of E.coli & Salmonella.
Interested in our supplements? Get your personalized quote now!
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